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She was born on September 13, 1787 at Paris.
Became Demoiselle d'honneur of Caroline Murat, she gave birth on December 13, 1806 to a boy named Charles-Leon, the natural son of Napoleon I.
Eleonore Denuelle de la Plaigne died on January 30, 1868 in Paris and was buried in the 41st division of the Pere Lachaise Cemetery .